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Thermal comfort in residences accounts for
2018-11-03

Thermal comfort in residences accounts for the well-being of the occupants and the impact on buy EDC.HCl consumption (Yoshino et al., 2006). However, once the building is built, altering the building structure/system elements to cater to thermal comfort needs will be difficult. Retrofitting studies
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NHS-SS-Biotin br Space syntax method for interpreting mosque
2018-11-03

Space syntax method for interpreting mosque layouts The space syntax method is an approach developed to analyze spatial configuration. Space syntax aims to describe spatial models (e.g., mosque layouts) and represent these models in numerical and graphical forms, thus facilitating scientific inte
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In this paper I define as poetic those functions
2018-11-02

In this paper I define as poetic those functions of responsive architecture whose purpose is not primarily instrumental. The meaning of poetics can be linked to that of ornament, traditionally an diazoxide Supplier of architecture without instrumental purpose or whose architectural significance had
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br Conclusion Cancer related fatigue is the most common
2018-11-02

Conclusion Cancer-related fatigue is the most common and crucial posttreatment concern among patients with cancer. It is not resolved by resting. Increasing evidence has suggested that activation of the caffeic acid has a critical role in CRF. The outcomes of current managements for CRF are contr
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br Health benefits of mushroom DF Compared to Asian countrie
2018-11-02

Health benefits of mushroom DF Compared to Asian countries such as China, Korea and Japan, the application of medicinal mushrooms in the Western countries is more recent [35–37]. Medicinal mushrooms are characterized by having cell wall polysaccharides and proteins as well as fungal secondary met
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br Introduction Dietary fibers demonstrated
2018-11-02

Introduction Dietary fibers demonstrated to have imperative role in improvement and management of human health, especially gastrointestinal system. However, type and source of dietary fiber greatly influence their functional properties. At present, the primary sources employed in food industries
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br Results br Discussion The results of
2018-11-02

Results Discussion The results of our study clearly demonstrate a correlation between age-related decrease in the quantity of tissue resident stem cells, and their impairment in self-renewal and differentiation capabilities. While equal amounts of tissue samples were analyzed, there was a subs
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br Discussion We have described an
2018-11-02

Discussion We have described an approach that achieves inducible, retrovirus-mediated gene expression by using the coding sequence of TFs fused to an ERT2 motif. Fusion of the ERT2 motif to two TFs that regulate fate-choice decisions in the course of adult neurogenesis (i.e., ASCL1 and NEUROD1) a
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Current hypotheses for this source draw on
2018-11-02

Current hypotheses for this source draw on diverse observations. Paneth 1 25-dihydroxyvitamin d3 are a favored epithelial source because they reside in intimate contact with Lgr5+ ISCs (Barker et al., 2007; Cheng and Leblond, 1974) and their coculture with the latter improves intestinal organoid for
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As male germline stem cells can
2018-11-02

As male germline stem hematoxylin can colonize recipient mouse testes (Brinster and Zimmermann, 1994), transplantation of isolated male germ cells into recipient mouse testes has been performed in various animal species including rodents and large animals (Clouthier et al., 1996; Dobrinski et al.,
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No effective therapies are available for motor neuron diseas
2018-11-02

No effective therapies are available for motor neuron diseases, including SMARD1. Neural stem cell (NSC) transplantation represents a possible therapeutic strategy for ameliorating the neurological phenotype by multiple mechanisms, including neuroprotection and cell replacement of different CNS neur
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hsp90 inhibitors Whereas most studies aiming at reprogrammin
2018-11-02

Whereas most studies aiming at reprogramming brain-resident glia into neurons focused on astroglia, NG2 glia represent an interesting alternative cellular source given their abundance and life-long capacity for proliferation (Dimou and Götz, 2014). Here, we found that ∼60% of the induced DCX+ neuron
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Here we sought to identify new druggable therapeutic targets
2018-11-02

Here, we sought to identify new druggable therapeutic targets for GBM. We combined transcriptome expression profiling and loss-of-function approaches to identify human kinases that play differential roles in PN and/or MES GSCs. Using a human kinome-wide lentiviral shRNA library, we identified 82 can
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Previous studies have reported that
2018-11-02

Previous studies have reported that Notch signaling controls the induction of neural stem ack1 inhibitor in vitro and in vivo during differentiation (Crawford and Roelink, 2007; Nelson et al., 2007). As established by Ogura et al. (2013), inhibition of this signaling pathway promotes the neuronal d
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Introduction Programmable nucleases are seeing widespread
2018-11-02

Introduction Programmable nucleases are seeing widespread application in the genome engineering field on account of their ability to permit precise genetic modifications in cell cultures and whole organisms. The CRISPR/Cas9 (CRISPR-associated) system (Bhaya et al., 2011) has attracted particular at
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