• Several in vivo and in

  2023-01-31

  

  Several in vivo and in vitro studies have demonstrated changes in bioactive lipid profiles under hyperglycemic conditions and have linked these changes with increased leukocyte adhesion and vascular dysfunction during diabetes. This input has originated partly from lipidomic studies that showed elev

• Infections inflammation and corneal transplant can all cause

  2023-01-30

  

  Infections, inflammation, and corneal transplant can all cause corneal neovascularization via upregulation of inflammatory cytokines, which attract myeloid ddhUTP into the cornea. These myeloid cells establish a cycle of cytokine secretion and further myeloid cell recruitment in the cornea. There ar

• 5 aminosalicylic acid Due to its unique histological archite

  2023-01-30

  

  Due to its unique histological architecture and blood supply, the lung is one of the most susceptible organs under uncontrolled systemic inflammatory circumstance [16]. Several studies have reported the anti-inflammatory benefits of metformin in acute lung injury induced by lipopolysaccharide (LPS)

• Globally the total number of patients included in

  2023-01-30

  

  Globally, the total number of patients included in the meta-analysis was 1885, ranging from 40 to 442 patients per study. All eligible studies reported the association between ALDH1 expression and patients' OS [24-26, 3241], whereas nine studies evaluated the relationship between ALDH1 expression an

• The present study determined the effect of DCA

  2023-01-30

  

  The present study determined the effect of DCA on VSMC calcification in vitro and in atherosclerotic ApoE-/- mice in vivo. We found that tepp non-toxic concentrations of DCA, did not affect VSMC viability, induced calcification of VSMC in culture and increased atherosclerotic vascular calcification

• To determine the post translation modifications

  2023-01-30

  

  To determine the post-translation modifications in chicken adiponectin, we isolated adiponectin from chicken adipose tissue by immunoprecipitation. Chicken adiponectin was then subjected to tryptic digestion and UPLC/MS/MS. The collagenous domain of chicken adiponectin was found to possess certain r

• tropisetron Evaluation of plant growth Transgenic Arabidopsi

  2023-01-30

  

  Evaluation of plant growth. Transgenic Arabidopsis plants were examined by microscope for alterations in cell size and shape. Overall plant architecture was also compared with control plants. Results and discussion Acknowledgments Introduction Mammalian ACK1 is a kinase effector for Cdc42

• Anti LT therapy by LO inhibition has been

  2023-01-30

  

  Anti-LT therapy by 5-LO inhibition has been hampered by occurring liver toxicities by Zileuton or the clinical phase II compound Atreleuton [36], [37] However both compounds possess a thiophene as well as an N-hydroxyurea moiety. These features could be linked with reactive thiophene intermediates [

• The relatively high concentration of

  2023-01-30

  

  The relatively high concentration of 5-HT used in this study (100 µM) is consistent with the concentrations used in other published ex vivo studies (Ropert and Guy, 1991, Passani et al., 1994, Shen and Andrade, 1998). In our paradigm 5-HT was focally applied at the surface of the slice via a fast pe

• During the year study period of

  2023-01-30

  

  During the 4-year study period, 19.9% of men in the dutasteride group developed prostate cancer as compared to 25.1% in the placebo group, which represents an absolute risk Phosphatase Inhibitor Cocktail 3 (100X in DMSO) australia of 5.1% for men taking dutasteride (Pe weighed against the prospect

• Introduction Cancer which is responsible

  2023-01-30

  

  Introduction Cancer, which is responsible for a million deaths each year, is universally feared, and approximately 50% of newly diagnosed cases can be cured [1]. The existing cancer treatments, including surgery, chemotherapy, radiotherapy or a combination of them, are quickly losing efficacy. The

• The inhibition of ACLY induces an anticancer effect

  2023-01-30

  

  The inhibition of ACLY induces an anticancer effect that has been reported to be involved in mitochondrial reactive oxygen species (ROS) generation [14], [16], dual blockade of mitogen-activated protein kinase and phosphatidylinositol-3-kinase/AKT pathways [11], and the glycolytic phenotype of tumor

• br Experimental Procedures br Acknowledgments This work was

  2023-01-30

  

  Experimental Procedures Acknowledgments This work was supported by NIH/National Human Genome Research Institute (NHGRI)R00 HG006922 and NIH/NHGRIR01 HG008974 (to J.G.), the Huntsman Cancer Institute, and the Women’s Cancers Disease-Oriented Team at the Huntsman Cancer Institute. Research repor

• br Acknowledgements This work is

  2023-01-30

  

  Acknowledgements This work is sponsored by the National Natural Science Foundation of China (grant no. 31201963) and Youth Backbone Teachers Project in Henan Province Department of Education, China (grant no. 2016GGJS-061). Introduction Acute lymphoblastic leukemia (ALL) is a malignant disord

• br Experimental All reagents were analytical grade and were

  2023-01-30

  

  Experimental All reagents were analytical grade and were used without further purification. The morphology was characterized using a field emission scanning electron microscope (Philips XL-30 FESEMFeSEM, ZEISS SUPRA 40VP, Germany). The hydrogel sample used for SEM analysis was freeze dried. All e

15868 records 330/1058 page Previous Next First page 上5页 326327328329330 下5页 Last page